' 
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
5
USERS' SCORE
Very Good
Based on 25 Reviews
8.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (From Lanolin)
1,250 mcg (50,000 IU)
6250%
Top Medical Research Studies
2
Vitamin D3 ineffective for CFS
Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial.
Directly tests treatment effectiveness
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.
Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.
In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.
In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More
8
Beta-glucan shows cognitive improvements
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Vitamin D3 effects unclear
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More
Most Useful Reviews
9.5
Improved alertness
I visited a therapist due to chronic fatigue syndrome and discovered I was deficient in vitamin D. This vitamin is crucial for maintaining healthy bones and the immune system. After replenishing my levels, my energy improved significantly, and I became more active.
Read More
9.5
Effective for immunity
Vitamin D3 is essential, especially for those like me with chronic fatigue syndrome and autoimmune conditions. It boosts immunity, alleviates depression, and benefits joint and muscle health. It's best taken with a fatty meal and vitamin K2 to aid absorption, showing significant improvements in my condition.
Read More
9.5
Reduced fatigue
Suffering from chronic fatigue syndrome and other symptoms, I found that vitamin D supplementation helped reduce my hair loss and depression. After eight weeks of treatment—one pill per week—my fatigue and joint pain lessened significantly, improving my overall well-being.
Read More
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Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
5
8
Beta-glucan shows cognitive improvements
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Vitamin D3 effects unclear
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More
2
Vitamin D3 ineffective for CFS
Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial.
Directly tests treatment effectiveness
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.
Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.
In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.
In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 25 Reviews
8.9
9.5
Improved alertness
I visited a therapist due to chronic fatigue syndrome and discovered I was deficient in vitamin D. This vitamin is crucial for maintaining healthy bones and the immune system. After replenishing my levels, my energy improved significantly, and I became more active.
9.5
Effective for immunity
Vitamin D3 is essential, especially for those like me with chronic fatigue syndrome and autoimmune conditions. It boosts immunity, alleviates depression, and benefits joint and muscle health. It's best taken with a fatty meal and vitamin K2 to aid absorption, showing significant improvements in my condition.
Read More
9.5
Reduced fatigue
Suffering from chronic fatigue syndrome and other symptoms, I found that vitamin D supplementation helped reduce my hair loss and depression. After eight weeks of treatment—one pill per week—my fatigue and joint pain lessened significantly, improving my overall well-being.
9.5
Improved alertness
Wonderful! I consulted a therapist about my chronic fatigue syndrome, and discovered a vitamin D deficiency. After completing the course, my tests returned to normal, and I feel more alert and active.
9.5
Enhanced overall health
This vitamin D product is excellent for addressing symptoms like chronic fatigue syndrome. With a prescription for the high dose of 50,000 IU, it's crucial to consult a doctor before use. After taking it weekly, I've seen overall health improvements, especially in my hair, bones, and joints.
Read More
